Development of a Energy-Saving Type of Organ (Cell) Supercooling Cryopreservation Apparatus through Innovative Integration of Advanced Technology Fields --- "Supermicrovessel Surgery" in the medical field, "Energy-Saving Type Supercooling Cryopreservation" in the engineering field, and "Preservation Technology for Supercooled Foods and Frozen Foods" in the food field --- adopted as one of the research business of industrial technology promoted by the New Energy and Industrial Technology Development Organization (NEDO).
Purpose of This Development
For the iatrogenic infertility caused by treatments for pediatric cancers, the societal demand for the research and development of cryopreservation of testes and ovaries is increasing. This project it to meet for this societal demand. This technology is expected to be available for other organs such as hearts and livers, so that it will greatly contribute to the innovation of the organ transplantation technology.
The Research Team and the Core Technology
The research team led by Dr. Mihara of the Faculty of Medicine and the team of Graduate School of Information Science and Technology, both of the Tokyo University, have found out the optimum frequency of varying magnetic field in relation to the theme called "The Relationship Between The Varying Magnetic Field And The Generation Of Supercooled State", which had been awaited for clarification. This clarification achieved by these teams enabled the generation of a stable supercooled state. The teams are further researching to establish organs (cells) freezing technology with which the cell destruction can be kept to the minimum level, utilizing said phenomenon of the generation of a stable supercooled state. Kabushiki Kaisha ABI's (Japan) supercooling technology by the generation of varying magnetic field of and Twinbird's Stirling refrigeration technology are combined to be the core technology of said research. By effectively using this core technology, we will strive to commercialize the organ preservation apparatuses which can preserve the organs for longer term.